![]() ![]() ![]() gigas (Thunberg, 1793) is a marine bivalve belonging to the phylum Mollusca, which contains the largest number of described marine animal species 1. Understanding marine biodiversity and its evolution remains a major challenge. Oceans cover approximately 71% of the Earth’s surface and harbour most of the phylum diversity of the animal kingdom. The oyster genome sequence fills a void in our understanding of the Lophotrochozoa. Our analyses also show that shell formation in molluscs is more complex than currently understood and involves extensive participation of cells and their exosomes. The expansion of genes coding for heat shock protein 70 and inhibitors of apoptosis is probably central to the oyster’s adaptation to sessile life in the highly stressful intertidal zone. Transcriptome studies reveal an extensive set of genes responding to environmental stress. ![]() The oyster genome is highly polymorphic and rich in repetitive sequences, with some transposable elements still actively shaping variation. Here we report the sequencing and assembly of the oyster genome using short reads and a fosmid-pooling strategy, along with transcriptomes of development and stress response and the proteome of the shell. The Pacific oyster Crassostrea gigas belongs to one of the most species-rich but genomically poorly explored phyla, the Mollusca. Nature volume 490, pages 49–54 ( 2012) Cite this article The oyster genome reveals stress adaptation and complexity of shell formation ![]()
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